中国冶金工业医学杂志

实时超声引导下徒手穿刺I-125粒子消融术在小肝癌治疗中的应用*

分类号：R 735.7

出版年,卷(期):页码：2025,42(2):135-137

摘要：

摘要：目的探讨实时超声引导下徒手穿刺在小肝癌患者I-125粒子消融术中的应用价值。方法收集甘肃省武威肿瘤医院肝病科2019—2022年就诊的70例小肝癌患者，按照不同的引导治疗方法将其分为超声组42例与CT组28例，比较两组的应用效果。结果超声组粒子植入治疗时间及穿刺针数均少于CT组（t＝－21.01、－4.67，均P＜0.05），术后出血率及术后气胸发生率均低于CT组（χ2＝5.06、9.70，均P＜0.05）。结论实时超声引导下徒手穿刺I-125粒子消融术在小肝癌的粒子植入治疗中安全可靠、操作可行、并发症少，值得推广。

Abstract：Objective To explore the value of real-time ultrasound guided freehand puncture in the I-125 seeds ablation for patients with small liver cancer. Methods A total of 70 patients with small liver cancer treated in the hepatology department of Wuwei tumor hospital from 2019 to 2022 were collected and divided into the ultrasound group （42 cases） and the CT group （28 cases） according to the guidance method used. The application outcomes were compared between the two groups. Results The ultrasound group had significantly shorter seed implantation times and fewer puncture needles compared to the CT group （t＝－21.01, －4.67, both P＜0.05）. Postoperative bleeding rates and pneumothorax incidences were also significantly lower in the ultrasound group than in the CT group （χ2＝5.06, 9.70, both P＜0.05）. Conclusion Real-time ultrasound-guided freehand puncture for I-125 seed ablation is safe, feasible, and associated with fewer complications in the treatment of small liver cancer, making it a valuable technique for clinical promotion.

基金项目：

?基金项目：甘肃省卫生健康行业科研项目（GSWSQN2021-011）；甘肃省中西医结合肿瘤临床研究中心开放基金（zlzx2021-5）；武威市科技局科技计划项目（WW2101113）

作者简介：

参考文献：

［1］程笑，黄静，李文飞，等.微波消融治疗小肝癌的效果分析［J］.中华肝脏病杂志，2021，29（11）：1059-1062.

［2 ］ Severin SE，Kulakov VN，Moskaleva EI，et al. The distribution of iodine-125 labeled alpha-fetoprotein in the animal organism and its accumulation in the tumor［J］. Vestn Ross Akad Med Nauk，2012（4）：11-15.

［3］ Ji Z，Jiang Y，Tian S，et al. The effectiveness and prognostic factors of CT-guided radioactive I-125 seed implantation for the treatment of recurrent head and neck cancer after external beam radiation therapy［J］. Int J Radiat Oncol Biol Phys，2019，103（3）：638-645.

［4］ Ji Z，Jiang Y，Guo F，et al. Safety and efficacy of CT-guided radioactive Iodine-125 seed implantation assisted by a 3 d printing template for the treatment of thoracic malignancies［J］. J Cancer Res Clin Oncol，2020，146（1）：229-236.

［5］ Wang H，Wang J，Jiang Y，et al. The investigation of 125I seed implantation as a salvage modality for unresectable pancreatic carcinoma［J］. J Exp Clin Cancer Res，2013（32）：106.

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