Abstract：Objective Objective to determine the safe and comfort-optimized ambulation protocol after femoral venous radiofrequency catheter ablation for paroxysmal supraventricular tachycardia（PSVT）. Methods A total of 142 PSVT patients undergoing femoral venous radiofrequency catheter ablation at The First Affiliated Hospital of Xi'an Jiaotong University from January to December 2023 were enrolled.According to admission order randomization by drawing lots,even-numbered cases were assigned to the control group（n＝71）and odd-numbered cases to the experimental group（n＝71）.The control group received conventional postoperative care, which included limb immobilization for 6 hours followed by turning in bed, and ambulation after 12 hours bed rest; The experimental group received bed repositioning at 2 hours postoperatively,turning in bed at 4 hours postoperatively, and ambulation after 6 hours of bed rest. Comparisons were made between the two groups regarding comfort scores at 12 hours postoperatively, back pain scores at 4, 6, 8, and 12 hours postoperatively, discomfort-related adverse reactions, and bleeding or hematoma incidence rates. Results At 12 hours postoperatively,comfort scores were significantly higher in the experimental group compared to the control group,with statistically significant differences（F＝11.959,P＜0.05）;Back pain scores in the experimental group decreased significantly after 4 hours postoperatively,while those in the control group peaked at 6 hours postoperatively and subsequently decreased,but remained significantly higher than those in the experimental group, the main effect of group, the main effect of measurement time,and the interaction effect between group and measurement time were significant（F＝91.123、87.450、8.880,all P＜0.05）; At 12 hours postoperatively, the incidence rates of discomfort-related adverse reactions were all significantly lower in the experimental group than in the control group, with statistically significant differences （χ2＝4.829、5.826,both P＜0.05）; The incidence of bleeding or hematoma showed no statistically significant difference between the experimental group and the control group （P＞0.05）. Conclusion Immobilization for 4 hours and bed rest for 6 hours improves postoperative comfort and reduces postoperative discomfort in PSVT patients undergoing femoral venous radiofrequency catheter ablation,without increasing the incidence of bleeding or hematoma,confirming its safety and efficacy.