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急性冠脉综合征的治疗进展
作者:刘欣        张英慧        方唯一 
单位:刘欣 张英慧(中国医科大学第八临床学院鞍钢铁东医院心内科 辽宁 鞍山 114002)方唯一(上海胸科医院心内科) 
关键词: 
分类号:R543.3
出版年,卷(期):页码:2005,22(1):0-0
摘要:
急性冠脉综合征(the acute coronary syndromes,ACS)已成为当今社会导致死亡的主要疾病之一,它包括不稳定型心绞痛(UA)、无Q波心肌梗死(MI)及有Q波心肌梗死.UA提示了稳定的冠脉病变已转变成另一种状态,即病人面临进展为MI或死亡的危险.UA通常是指[1]:(1)首次出现的心绞痛:在最近4~8周内出现的首次缺血性胸痛,至少为加拿大心绞痛分级Ⅲ级;(2)逐渐加重的心绞痛:即心绞痛发作较前更频繁、更严重或时间更长,或对硝酸甘油不敏感;(3)休息时心绞痛:即休息时出现心绞痛发作.
基金项目:
作者简介:
参考文献:
Theroux P.Fuster V Unstable angina and non - Q- wave myocardial infarction 1998 Braunwald E Unstable angina. A classification 1989 Maggioni AP.Schweiger C The diagnostic - therapeutic processes in patients with unstable angina in Italy:results of the EARISA registry 1998(zk) Ronner E.Dykun Y.van den Brand MJBM Platelet glycoprotein of unstable coronary syndromes and coronary intervention 1998 PURSUIT Trial Investigators Inhibition of platelet glycoprotein Ⅱ b/Ⅲ a with eptifibatide in patients with acute coronary syndromes 1998 Yusuf S.Flather M.Pogue J Variations between countries in invasive cardiac procedures and outcomes in patients with suspected unstable angina or myocardial infarction without initial ST elevation 1998 Ridker PM.Haughie P Prospective studies of C-reactive protein as a risk factor for cardiovascular disease 1998 Theroux P.Fuster V Acute coronary syndromes - unstable angina and non- Q wave myocardial infarction 1998 The PRISM study investigators A comparison of aspirin plus tirofiban with aspirin plus heparin for unstable angins 1998 The PRISM - PLUS Study Investigators Inhibition of the platelet glycoprotein Ⅱ b/Ⅲ a receptor with tirofiban in unstable angina and non - Q - wave myocardial infarction 1998 The PARAGON investigators An international, randomized,controlled trial of lamifiban,a platelet plycoprotein Ⅱ b/Ⅲs inhibitor,heparin or both in unstable angina 1998 The OASIS Registry Investigators Variations between countries in invasive cardiac procedures and outcomes in patients with suspected unstable angina or myocardial infarction without initial ST elevation 1998 Boden W.O'Rourke R.Crawford M Outcomes in patients with acute non - Q - wave myocardial infarction randomly assigned to an invasive as compared with a conservative management strategy 1998 The STRESS Investigators Coronary stenting versus balloon angioplasty for unstable angina 1998 The Epistent investigators Randomized placebocontrolled and balloon- angioplasty - controlled trial to assess safety of coronary stenting with use of platelet glycoprotein Ⅱ b/Ⅲ a blockade 1998 Boden WE.O'Rourke RA.Crawford MH Outcomes in patients with acute non - Q - wave myocardial infarction randomly assigned to an invasive as compared with a conservative management strategy 1998 Akkerhuis M.Boersma H.Harrington R In patients with acute coronary syndromes without ST elevation, eptifibatide particularly reduces complications in those under going early percutaneous intervention (Abstr) 1998(zk) Kereiakes D.McDonald M.Abbottsmith C Cost efficient stenting: a multi - faceted approach 1998(zk) Leon MB.Baim DS.Popma J J A clinical trial comparing three antithrombotic - drug regimens after coronaryartery stenting. Stent Anticoagulation Restenosis Study Investigators 1998 Urban P.Macaya C.Rupprecht HJ Randomized evaluation of anticoagulation versus antiplatelet therapy after coronary stent implantation in high - risk patients: the multicenter aspirin and ticlopidine trial after intracoronary stenting (MATTIS) 1998 Bertrand ME.Legrand V.Boland J Randomized multicenter comparison of conventional anticoagulation versus antiplatelet therapy in unplanned and elective coronary stenting. The full coagulation versus aspirin and ticlopiding (FANTASTIC) study 1998 Kong DF.Califf RM.Miller DP Clinical outcomes of therapeutic agents that block the platelet glycoprotein Ⅱ b/Ⅲ a integrin in ischemic heart disease 1998 Phillips DR.Scarborough RM Clinical pharmacology of eptifibatide 1997 Chierchia Current therapeutic strategies in unstable angina 1999
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