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电子期刊 >> 正文 |
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摘要：
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目的:探讨血清同型半胱氨酸(Hcy)、脂蛋白(a)[LP(a)]、起敏C反应蛋白(hs-CRP)的变化与冠状动脉粥样硬化及其程度的关系.方法:应用冠状动脉造影判定144倒患者冠状动脉粥样硬化及其程度,同时抽取患者血液测定血清中Hcy、LP(a)及hs-CRP的水平.结果:冠状动脉粥样硬化的患者血清Hcy、LP(a)及hs-旻RP的水平比冠状动脉正常的患者明显增高,二者有显著性差异(P＜0.01);且血清Hcy、LP(a)及h-CRP的水平随病变支数增加而增高.结论:Hcy、LP(a)、hs-CRP作为独立的动脉粥样硬化危险因素对冠心病的诊断及程度的判定有积极的临床意义.
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参考文献：
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Sacco RL.Roberts JK.Jacobs BS Homocysteine as a risk factor for ischemic stroke: an epidemiological story in evolution 1998(4) Hak AE.Stehouwer DA.Bots ML Association of C- eactive protein with obesity, insulin resistance, and subclinical atherosclerosis in healthy middle-aged women 1999 Finkelstein JD The metabolism of homocysteine: pathways and regulation 1998 Guthikonda S.Haynes WG Homocysteine as a novel risk factor for atherosclerosis 1999 Selhub J.D Angelo A Relationship between homocysteine and thrombotic disease 1998(2) Haidari M.Javadi E Evaluation of C- reaction protein, a sensitive maker of inflammation, as a risk factor for stalble coronary disease 2001
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