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电子期刊 >> 正文 |
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摘要：
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目的:观察小儿先心肺高压在心内直视手术麻醉期间,不同通气模式对呼吸功能的影响.方法:将24例中度肺高压(M 组)和24例重度肺高压(S 组)的先心病患儿随机各分为三组:M1、S1组为 PCV 通气组;M2、S2组为 PCV+PEEP(2cmH2O)通气组;M3、S3组为 PCV+PEEP(4cmH2O)通气组.测定各组各时点的呼吸系统总顺应性(Crs)及肺表面活性物质(PS)生化指标.结果:与诱导插管后、体外循环(CPB)转流前比较,M1、M2组以及 S1\,S2组体外循环转流后和术毕的 Crs 值有显著下降(P＜0.01),而 M3和 S3组前后比较则 Crs 值无明显改变;M1、M2组以及 S1、S2组体外循环转流后和术毕的 SatPC/TP、SatPC/TPL 比值下降显著(M1、S1组,P＜0.01;M2、S2组,P＜0.05),而 M3和 S3组 SatPC/TP、SatPC/TPL 比值无明显改变.结论:采用4cmH2O 的 PEEP 对于防止术后肺功能的进一步恶化有效.
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