Objective:To study the distributive characters of T704C of angiotensinogen(AGT)gene′s single nucleotide polymorphisms(SNP),and to investigate the association between AGT gene SNP and intracerebral hemorrhage(ICH).Methods:A case-control study of 70 cases and 89 controls were carried out with polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP).The AGT genotype and gene frequencies were analyzed,and further analysis were conducted according as they were hypertensive or without hypertension.Distributive differences of AGT genotype and allele frequencies were analyzed in the case group and control group,then concluded whether this hereditary factor could lead to ICH.Results:Three genotypes in site 704 of AGT gene were identified among 169 individuals.The CC genotype's frequency of AGT gene was 0.414 in cases and 0.348 in controls(P>0.05);The C allele frequency of AGT gene was 0.671 in cases and 0.612 in controls(P>0.05);and there were no significant difference in the frequencies of CC genotypes and C allele between the two subgroups of ICH(P>0.05).Conclusions:AGT T704C SNP existed in our population group and AGT T704C SNP was not associated with the occurance of ICH.