中国冶金工业医学杂志

大肠息肉的异型增生及癌变分析

作者：陈萍杨希宁王涛

关键词：大肠息肉异型增生恶变

分类号：R 735

出版年,卷(期):页码：2010,27(4):379-380

摘要：

目的：研究息肉间变的相关因素。方法：总结529例息肉及其中伴异型增生或恶变息肉的分布、大小及病理资料。结果：529个息肉异型增生达3081%，息肉恶变达302%，好发于左半结肠。异型增生及恶变息肉随息肉增大而增加，息肉恶变率直径06~10 cm 者为125%，11~19 cm 为125%，≥20 cm 为75%，腺瘤性息肉明显多于非腺瘤性息肉，其异型增生为5962%，恶变率为592%，非腺瘤性息肉异型增生077%，恶变率为0，其中，腺瘤中又以绒毛状腺瘤及绒毛管状腺瘤的异型增生及癌变最多见。结论：息肉间变与息肉的大小、形态和类型有密切关系。

The analysis for characteristics of canceration in colon polypsCHEN Ping,YANG Xi\|ning,WANG TaoDepartment of Gastroenterology,The Central Hospital of Maanshan,Maanshan,243000 Abstract Objective:The factors which affect polyp\|carinoma sequence were discussedMethods:529 colorectal polyps were reviewed and all data on endoscopy and pathology were analysedResults:Among 529 polyps,3081% cases were the gravis atypical hyperplasia and 302% cancerousThe rate of canceration seemed to depend on its dimensions,being 125%,125%and 75% for the 06~10,11~19 and≥20 cm in size,respectivelyThere was a significant difference between the incidence in gravis hyperplasia and cancerous polyps than in other polyps,which was 5962% and 592%,the other 077% and 0There was a high canceration of polyps in villous adenomas and mixed polypsConclusions:The maglignant transformation of polyps was reactived with enteroscopic and  pathological characteristics of colorectal polyps Key WordsColon polyp；Dysplasia；Carcinoma

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作者简介：

参考文献：

1 Jass JnColorectal cancer:a multipathway diseaseCrit Rev Oncog,2006,12(3\|4):273
2 郑芝田胃肠病学\[M\]3版，北京：人民卫生出版社，2000：846\|852
3 陈春华，邱立华大肠息肉1854例患者的临床观察及恶变特征分析肿瘤防治杂志，2005，12（24）：1888
4 Repici A,Tricerri REndoscopic polypectomy:techniques,complications and follow\|upTech Coloproctol,2004,8(Suppl 2)：s283

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