中国冶金工业医学杂志

米非司酮配合聚维酮碘液介入治疗卵巢子宫内膜异位囊肿42例

作者：罗彬唐晓惠

分类号：R 815

出版年,卷(期):页码：2010,27(4):383-384

摘要：

目的：观察米非司酮配合超声介入聚维酮碘液（povidone iondine，PI）治疗子宫内膜异位囊肿的疗效。方法：对72例盆腔子宫内膜异位囊肿的患者在阴道超声引导下行囊肿穿刺、抽吸并注射PI进行治疗。治疗组42例于当日起口服米非司酮（250 mg，qd）3~6个月；对照组30例单行囊肿注入PI治疗。随访2年，比较两组治疗后的复发率及米非司酮的辅助治疗和副反应。结果：治疗组和对照组的复发率1年各为48%和267%，2年各为71%和300%。两组对比有显著差异（P＜001），治疗组1年和2年复发率比较无显著差异（P＞005）。结论：加用米非司酮治疗3~6个月可有效地降低子宫内膜异位囊肿穿刺注入治疗的复发率，副反应小，是一种安全高效尤对手术后复发盆腔粘连不宜手术的患者适用。

Clinical study for mifepristone combination with povidone lodine to treat heterotopic endmetrial cystLUO Bin,TANG Xiao\|huiDepartment of Gynaecology and Obstetrics,Pangang Midi Hospital Panzhihua 617063
Abstract Objective:The obsevation of effective treatment to heterotopic endmetrial cyst by mifepristone and ultrasound guided puncturing matching with povidone lodine solutonMethods:To the 72 patients of pelvic heterotopic endmetrial cyst,the treatment was using the vagina ultrasound guided puncturing to paracentesis,suction and inject povidone lodine soluton on the cyst42 cases of treatment group oral mifepristone(250mg)3 to 6 months from the first day,the other 30 cases of control group were injected povidone lodine soluton on the cystThrough 2\|years follow\|up,compared the relapse rate of the two groups after using different treatments,and the adjuvant therapy and the side effects of mifepristoneResults:The 1\|years relapse rates of treatment group and control group were 48% and 267% respectively,2\|year's relapse rates were 71% and 300% respectivelyThe two groups were different significantly(P＜001);Treatment group for the relapse rates of the one years and the two years showed no significant difference(P＞005)Conclusions:When the doctor using the treatment of suction and injection on heterotopic endmetrial cyst,if plusing with mifepristone for 3 to 6 months,the relapse rates would be effective reduced,and the side effects were lessSo it could be seen as a safe and effficent treatment,especially suitable for the patients who had a recurrence of pelvic adhesions merged post\|operative after surgery.
Key WordsHeterotopic endmetrial cyst;Ultrasound guided puncturing;Povidonelodine soluton;Mifepristone

基金项目：

作者简介：

参考文献：

1 罗丽兰子宫内膜异位症中华妇产科学（下册）北京：人民卫生出版社,1999：1264
2 冷金花，郎景和，杨佳欣,等子宫内膜异位症的诊断进展中华妇产科杂志，2000，35（1）：53
3 Finam MA,Kwcak JA,Joseph GF,et alSurgical resection of endometriosis after prior hysterectomyJ La Stste Med Sco,1997,149:32
4 消毒防腐药聚维酮碘中华人民共和国药典见：临床用药须知国家药典委员会编北京：化学工业出版社，2000：910
5 郭海燕，周世梅实用妇产科药物治疗学北京：人民出版社，1999：208
6 Kattel LM,Ulmann A,Murphy AA,et alTreatment of endometriosis with the antiprogesterone mifepristoneFertil steril,1996,65(1):23
7 鲍先范重度子宫内膜异位症患者术后应用米非司酮与丹那唑的临床比较中国冶金工业医学杂志，2003，20（4）：247\|249

服务与反馈：

【文章下载】【加入收藏】