To evaluate the safety of peri\|operative  periods with combined epidural subarchnoid analgesia  for the aging PatientMethods:The anesthesia was perfected with combined spinal epidural analgesia in the 40 presentsEstimate  spinal block level to T10\|C1,gave with  epidural catheter at same pointsmonitor vital signs and urine outputAdjust fluids to keep urine output at 1ml/kg/hrMonitoring of heart rate,mean arterial pressure,SpO2,PetCO2,and patient controlled epidural analgesia(PCEA)were perfected Simultaneously through perioperative periodResults:(1)Onset time,thorcic10 pain\|free time,time of reaching to the highest nerve block level were （3672±250）sec、（373±010）min和(614±022)min,,respectivelyThe highest nerve block level were thoracic 810±050(2)There are no significant differences in hemodynamic monitoring of heart rate(HR)、systolic blood pressure(SBP)、diastolic blood pressure(DBP)、 mean arterial pressure（MAP）and SpO2 between the before and after anesthesia,end after anesthesia maintained with spinal epidural anesthesia(3)Hypotension occur in at 8 cases(20%)after anesthesia,and were effectively corrected by ephedrine,Nausea was 4(10%)case,during and operation(4)postspinal headache were 2(5%)cases,urinary retention were 0 cases,respectively(5)Time of nerve block fade to thoracic10 time that lower limbs were able to recovery sensory and time of epidural anesthetic were 15820 732min and 12000 3080min,respectivelyThe combined spinal epidural analgesia  than whether spinal or epidural anesthesia could safe and effective used for aging patient05%Hyperbaric bupivacaine\|glucose mixture could safe and effective used for spinal anesthesia,its pH value was 50;density of 075% and 05%bupivacaine\|glucose mixture were 1010 and 1018,respectivelyConclusions:There were some advantage during To evaluate the safetility of perioperative period with combined epidural subarachnoid analegsia the forty for aging Patient