中国冶金工业医学杂志

中晚期胃癌介入治疗的临床研究

关键词：中晚期胃癌介入治疗

分类号：R 7352文献标志码：A文章编号：1005-5495(2012)01-0

出版年,卷(期):页码：2012,29(1):10-12

摘要：

摘要：目的探讨介入治疗在中晚期胃癌患者的治疗效果及耐受性。方法介入组（治疗组）30例患者行股动脉穿刺插管，腹腔动脉造影，确定位置，向靶血管内注入化疗药物及栓塞剂的治疗，并与静脉化疗组（对照组）20例进行效果及毒副反应比较。结果治疗组有效率高于对照组，治疗组中腹痛、腹胀及进食梗噎缓解改善的更为明显，与对照组比较差异有统计学意义。两组间比较恶心、呕吐及白细胞下降差异有统计学意义，对照组重于治疗组。结论动脉介入化疗不仅有较高的局部缓解率，而且毒副反应轻，患者的耐受性及依从性好，提高了患者的生活质量，是治疗中晚期胃癌的一种新方法。

Abstract:Objective To evaluate the efficacy and tolerance of the interventional treatment of advanced gastric cancer.MethodsThey were assigned to the interventional treatment group(30 patients were treated with interventional treatment)and the intravenous chemotherapy group(20 patients who were treated with intravenous chemotherapy).The clinical efficacy and side effects were observed. ResultsThe clinical efficacy of the interventional treatment group was better than that of the intravenous chemotherapy group,the relief for abdominal pain,abdominal distension.swallow stem choke sense after interventional treatment in the patients with advanced gastric cancer were better than that of the interventional treatment.The nausea,vomiting and eukopenia of the intravenous chemotherapy group were more severe than that of the interventional treatment group.ConclusionArterial Infusion of Chemotherapy was a newer treatment way to advanced gastric cancer，which could increase remission rates,improved the quality of life of patients,reduced the side effects and were more likely to get accepted by patients.

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参考文献：

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［2］Noh SH,Yoo CH,Chung HC.Early postoperative intraperitoneal chemotherapy with mitomycin C,5-fluorouracil and cisplatin for advanced gastric cancer[J].Oncology,2001,60(1):24-30.
［3］刘福坤.介入治疗在胃肠道肿瘤中的应用[J].腹部外科，2004，17（5）：267-269.
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