Abstract: Objective To assess the risk factors related to the prevalence of peripheral arterial disease(PAD)in type 2 diabetes mellitus(T2DM).Methods The 804 cases with T2DM in hospital were enrolled.Compare the clinical data between PAD group and non\|PAD group.The prevalence of PAD in different courses of T2DM and its related risk factors were analyzed by logistic regression model. Results(1)There were significant differences in ages,HbA1C,Urinary albumin creatinine ratios,serum creatinine,LDL-C,SBP,DBP and courses of T2DM between PAD group and non\|PAD group.(2)The prevalence of T2DM in hospital was 33.5%(no difference between males and females).The prevalence of PAD was significantly increased when the course of T2DM above 10 years(χ2=11191,P=0.011).The prevalence of PAD in hypertension group was much higher than its in normal blood pressure group(439%vs223%;χ2=42123，P＜0.001).The abnormal rate of urinary albumin creatinine ratios in T2DM was 407%(301/739).The rate of dominant proteinuria was 96%(71/739).Compared to normal proteinuria group,the prevalence of PAD in dominant proteinuria group was much higher(535%vs294%;χ2=15.588，P＜0001).(3)It was showed that the abnormal urinary albumin ratios,aging and hypertension were risk factors related to the prevalence of PAD in T2DM in hospital by logistic stepwise regression analysis.Conclusion The prevalence of PAD was significantly increased when the course of T2DM above 10 years,the abnormal urinary albumin ratios,aging and hypertension were risk factors related to the prevalence of PAD in T2DM.