Abstract: Objective To evaluate the effect of laser photocoagulation for diabetic retinopathy treatment.Methods 81 eyes of 46 diabetic retinopathy cases were treated with the line of laser photocoagulation in recent 4 years at our hospital.Regular visual acuity,fundus examination,fundus fluorescein angiography(3-4 months after treatment)were done.Neovascularization,retinal hemorrhage,bleeding out,vitreous hemorrhage,etc.were recorded.All cases were observed for 4 months to 3 years.Results The changes of visual acuity after retinal photocoagulation treatment in 1 month increased much more than 2 lines in 48 eyes,had no change in 26 eyes,decreased more than 2 lines in 20.Microaneurysms were almost regressed in 52 of 81 eyes under the effective photocoagulation points with fundus observation by the FFA and ophthalmoscopy after 1 to 2 months,gradually subsided in 6 eyes after re\|added photocoagulation.There were no changes in 8 eyes.And those were developed as proliferative diabetic retinopathy in 2 cases;recurring small hemorrhage were getting absorbed after supplemented laser photocoagulation in another 4 to 8 months.Conclusion Laser photocoagulation treatment for diabetic retinopathy was an effective method.