Abstract:ObjectiveThe aim of this study was to evaluate the diagnosis value of fused single\|photon emission computed tomograghy and computed tomograghic images in bone metastasesMethods150 patients were chosed,and 192 lesions were detected on 99mTc\|MDP whole body bone imaging and were interpreted separately on fused SPECT\|CT images and single CT reconstruction images.29 patients were followed up or received additional examinationThe differences of the diagnosis of SPECT\|CT fused images and CT images were analyzedResults192 lesions detected on fused images,74 were malignant and 89 were benign lesions,only 29 were suspensed;fused images had significant differences with single CT(P＜001)29 patients with definite diagnosed，the diagnostic sensitivity，specificity，accuracy rate，of fused SPECT and CT images were 933％，857％，897％，while single CT images were 846%,688%,759%，respectively.ConclusionSPECT and CT image fusion analysis has high value in differentiation of bone metastasis from benign lesions;enhance the confidence of images diagnosis and greatly improve the value of clinic application.