中国冶金工业医学杂志

氯吡格雷联合低分子肝素治疗短暂性脑缺血发作的疗效观察

作者：王莉

分类号：中图分类号：R 743.33文献标志码：A文章编号：1005-54

出版年,卷(期):页码：2013,30(3):251-252

摘要：

摘要：目的观察氯吡格雷联合低分子肝素治疗短暂性脑缺血发作的临床效果。方法将近年来在我院就诊的82例短暂性脑缺血发作患者分为观察组和对照组各41例，两组均采用常规方法治疗，观察组在此基础上加用氯吡格雷与低分子肝素治疗。结果观察组总有效率为90.2%，明显高于对照组65.9%的总有效率（P＜0.05）；治疗后，观察组患者的PT和PLT水平与治疗前比较有统计学差异（P＜0.05），而且PLT水平与对照组比较亦有统计学差异（P＜0.05）。结论在常规治疗的基础上加用氯吡格雷与低分子肝素治疗短暂性脑缺血发作疗效显著，用药安全，可有效控制短暂性脑缺血发作及降低血栓形成的机率。

Abstract:ObjectiveTo observe the clinical effect of Clopidogrel combined with Low molecular weight heparin in the treatment of transient ischemic attack.MethodsEighty\|two transient cerebral ischemic attack(TIA)patients in our hospital were divided into the observation group and the control group,and 41 cases in each group.Conventional treatments were used in both group,and additional treatment of Clopidogrel combined with Low molecular weight heparin was taken in the observation group.ResultsThe total effective rate in the control group was 90.2%,higher than 65.9% of the control group,and there was a significant difference(P＜0.05).The PT detection in the observation group after treatment was significantly higher than that before treatment.After treatment,PLT was significantly Lower than before treatment;there were significant differences (P＜0.05).ConclusionClopidogrel combined with Low molecular weight heparin based on the conventional treatment for TIA patients is safe and effective significantly,and it can effectively control TIA,reduce the probability of thrombus formation.

Key Words:Clopidogrel;Low molecular weight heparin;Transient ischemic;Clinical effect

基金项目：

作者简介：

参考文献：

[1\]苏凯.短暂性脑缺血的中西医防治要点\[J\].光明中医，2010，25(10)：1891\|1892.

[2\]刘苏平.短暂性脑缺血发病相关因素分析\[J\].按摩与康复科学，2011，2 (10)：90.

[3\]毕连红，于国刚.脑血管疾病并发脑心综合征的临床研究\[J\].求医问药（下半月刊），2012，10(6)：328\|329.

[4\]陈斌.短暂性脑缺血发作临床诊治探讨\[J\].右江民族医学院学报，2012，34(1)：25\|26.

\[5\]黄森权，罗林佳.低分子肝素治疗短暂性脑缺血临床研究\[J\].临床和实验医学杂志，2009，8(2)：29\|30.

\[6\]周曼云，姚绍鑫.低分子肝素与普通肝素治疗短暂性脑缺血发作疗效比较\[J\].中国老年学杂志，2011，31(7)：1137\|1138.

\[7\]马玉龙.脑缺血发作伴脑梗死的临床治疗与分析\[J\].当代医学，2010，16(1)：58.

服务与反馈：

【文章下载】【加入收藏】