Abstract:ObjectiveTo observe the efficacy and safety of hydrocortisone butyrate cream combined with recombinant human epidermal growth factor gel in treatment of infantile eczema.MethodsDivided the selected 96 patients of infantile eczema into two groups randomly,hydrocortisone butyrate creams were used combined with recombinant human epidermal growth factor gel twice per day alternatively，and was maintained after the rash cured later in the treatment group.Hydrocortisone butyrate creams were used only twice per day and the therapy was changed to once every day after the rash disappeared in the control group.The courses of treatment in both groups were 14 days.The variations of the rash were recorded in 7，14 days after medication and 7 days after recovery.ResultsAt 7 days after therapy,the effective rates in the treatment group and the control group were respectively 78% and 67.39%.There were no significant difference between two groups(P＞0.05).Which were 94% and 80.44% after 14 days of therapy. There were significant differences(P＜0.05).The relapse rate in the treatment group was 7.89%,and in the control group was 3929%.ConclusionIt is a very effective,low recurrence and safe method that hydrocortisone butyrate cream combined with recombinant human epidermal growth factor gel in treatment of infantile eczema.