中国冶金工业医学杂志

孟鲁司特钠治疗儿童支气管哮喘临床疗效观察

作者：董质冰汪晓婷罗丽明

分类号：中图分类号：R 562

出版年,卷(期):页码：2014,31(3):254-255

摘要：

摘要：目的探讨孟鲁司特钠治疗儿童支气管哮喘的临床疗效。方法将128例轻中度支气管哮喘患儿分为观察组73例和对照组55例，均接受综合治疗，观察组同时加用孟鲁司特钠；观察比较两组患儿症状和体征缓解情况、哮喘复发率等，并分析不同诱因的哮喘患儿加用孟鲁司特钠的效果。结果与对照组相比较，观察组患儿咳嗽、喘息消失的时间明显缩短，复发率显著降低，且尤其以感染、特定过敏原及剧烈运动为哮喘发作诱因的患儿效果更好。结论布地奈德、复方异丙托溴铵和孟鲁司特钠联合应用，可迅速缓解哮喘患儿的咳喘症状、缩短病程、降低复发率，在儿童哮喘的治疗过程中具有协同作用。

Abstract:ObjectiveTo investigate the clinical curative effects of montelukast(MK)on pediatric asthma.MethodsOne hundred and twenty\|eight children were divided into experimental groups(73 cases)and control group(55 cases),all of them were received comprehensive treatment.Moreover,the experimental group increased MK in their therapeutic plan.Compare the curative effect between these two groups of children with asthma symptoms and the recurrence rate.To observing the MK curative effect among different incentives of asthma.ResultsCompared with the experimental group the symploms of asthma were disappeared more early than control group,and the recurrence rate were reduced,especially in the incentives was infection or allergy or strenuous exercise of asthmatic children.ConclusionBudesonide,compound ipratropium bromide and MK combined therapy can relieve symptoms quickly,shorten the course of asthmatic bronchitis,and decrease the recurrence rate.Synergistic effect was received base on the comprehensive treatment with MK.

基金项目：

作者简介：

参考文献：

\[1\] 全国儿科哮喘协作组2000年与1990年儿童支气管哮喘患病率的调查比较\[J\]中华结核和呼吸杂志,2004,27(2)：112\|116

\[2\]陈强,李莉儿童哮喘危重状态的治疗\[J\]实用儿科杂志,2012,27(4)：310\|312

\[3\]中华医学会儿科学会呼吸学组，《中华儿科杂志》编辑委员会，The Subspecialty Group of Respiratory Diseases TSoPCMA，等儿童支气管哮喘诊断与防治指南\[J\]中华儿科杂志，2008，46（10）：745\|753

\[4\]李福,罗文娟,赵晓瑞,等儿童支气管哮喘发病的危险因素分析\[J\]临床儿科杂志， 2013，31(4)：384

\[5\]Behrens TCurrent trends in aetiological asthma research\[J\]Eur J Epidemiol，2009，24(3)：115\|118

\[6\]王晓艳糖皮质激素吸入治疗疗程对哮喘儿童肺功能的影响\[J\]中国妇幼保健,2013,28（1）：186\|188

\[7\]李兰,王智斌,蒋虹,等孟鲁司特对呼吸道合胞病毒毛细支气管炎患儿血清半胱氨酰白三烯的影响\[J\]临床儿科杂志，2009，27(9)：883\|885

服务与反馈：

【文章下载】【加入收藏】