中国冶金工业医学杂志

高血压患者血压晨峰与颈动脉硬化的相关性分析

作者：张玲

分类号：R 544.1

出版年,卷(期):页码：2015,32(5):497-498

摘要：

目的探讨高血压患者血压晨峰与颈动脉硬化的相关性。方法选取原发性高血压患者200例，应用动态血压监测仪记录24小时血压，根据测得血压结果分为血压晨峰组112例和非血压晨峰组88例，两组均采用彩色多普勒检查颈动脉中层厚度，并观察颈动脉斑块数量情况。比较两组颈动脉内膜中层厚度及颈动脉斑块数量上的差别。结果血压晨峰组颈动脉内膜中层厚度（1.22±0.25）mm，非血压晨峰组颈动脉内膜中层厚度（1.01±0.18）mm，两组进行比较，差异有统计学意义（P＜0.05）。血压晨峰组颈动脉斑块检出率为77.6%，斑块平均厚度为（1.86±0.19）mm，多发斑块检出率43.75%，而非血压晨峰组颈动脉斑块检出率58.6%，斑块平均厚度为（1.42±0.18）mm，多发斑块检出率28.41%，两组比较差异有统计学意义（P＜0.05）。结论原发性高血压患者血压晨峰是颈动脉硬化的重要危险因素。

关键词：高血压；血压晨峰；颈动脉硬化；颈动脉斑块

ObjectiveTo investigate the relationship between morning blood pressure surge and carotid atherosclerosis in hypertension patients.Methods200 patients with essential hypertension by ambulatory blood pressure monitoring,recording 24 hour blood pressure,according to the results of blood pressure measurement,the patients were divided into morning blood pressure surge group(n=112)and non morning blood pressure surge group(n=88).Carotid artery intima\|media thickness was examined by color Doppler in two groups and the number of carotid artery plaque was recorded.The difference of carotid artery intima\|media thickness and the number of carotid artery plaque in two groups were compared.ResultsThe carotid artery intima\|media thickness in morning blood pressure surge group was(1.22±0.25)mm,in non morning blood pressure surge group was(1.01±0.18)mm,the difference was statistically significant(P＜0.05).The detection rate of carotid artery plaque in morning blood pressure surge group was 77.6%,the mean patch thickness was(1.86±0.19)mm,detection rate of multiple plaque 43.75%,and in non morning blood pressure surge group,the detection rate of carotid artery plaque was 58.6%,average patch thickness was(1.42±0.18)mm,the detection rate of multiple plaque was 28.41%.Comparing that in two groups,there were significant differences(P＜0.05).ConclusionMorning blood pressure surge is an important risk factor for carotid atherosclerosis in patients with essential hypertension.Key Words:Hypertension;Morning blood pressure surge;Carotid atherosclerosis;Carotid artery plaque

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