设为首页    加入收藏   
首页期刊介绍编委会投稿须知稿约期刊订阅广告合作联系我们留言板

《中国冶金工业医学杂志》 欢迎访问,欢迎查询,欢迎引用!本刊已开通手机短信发送录用通知业务。敬告作者投稿成功的标志是收到手机短信和邮件回执。投稿出现问题邮箱wangtaohong@wangkantong.com,网站技术支持QQ1172987239。

本刊对投稿新要求:1.如果作者是第一次投稿,请务必用自己邮箱注册,并请认真填写作者单位详细通讯地址和第一作者手机,以便能及时准确收到杂志。2.文章必须有中文摘要,近5年参考文献至少3条。详见本刊投稿须知。本刊已同“中国知网”签订独家上网协议。

本刊2022年第3期杂志正在快递寄出,如果有作者没有收到杂志请与本刊快递员白先生联系,电话13304129493,说明第一作者姓名和联系方式。

本刊2022年第3期杂志基本信息已经登载在本刊网站,欢迎读者、作者查询引用。

氨甲环酸减少单节段腰椎融合术后失血量的临床研究
作者:刘涛 刘玉平 
单位:滕州市中心人民医院骨科 山东 滕州 277500 
关键词:氨甲环酸 腰椎融合 出血 血栓 
分类号:R 6815
出版年,卷(期):页码:2018,35(3):260-262
摘要:

 目的探讨局部应用氨甲环酸对减少单节段腰椎融合术术后出血的影响。方法选取本科室2015年11月至2017年1月拟行单阶段腰椎融合术的患者78例,随机分为对照组和实验组,每组各39例。实验组在关闭切口前将1 g氨甲环酸加入生理盐水配置成20 ml混合液给予切口内及切口周围注射,对照组给予相同剂量生理盐水注射。比较两组患者术前、术后血红蛋白、红细胞压积、术中失血量和术后引流量、D\|二聚体和活化的部分凝血活酶时间等凝血指标的变化以及两组输血患者的数量,同时观察患者是否出现下肢深静脉血栓症状。结果实验组患者术后血红蛋白、红细胞压积、术后引流量、输血例数均较对照组明显减少,差异有统计学意义(P<005)。两组患者术后均未发现下肢深静脉血栓形成。结论局部应用氨甲环酸能明显减少腰椎单节段融合术后的失血量及输血量,且不增加下肢静脉血栓形成的风险。关键词:氨甲环酸;腰椎融合;出血;血栓

 Abstract:ObjectiveTo investigate the effect of topical application of tranexamic acid on the reduction of bleeding after single stage lumbar fusion Methods78 undergoing single segment lumbar fusion in our department from November 2015 to January 2017 was selected,and  randomly divided into control group and experimental group(n=39) 20 ml mixed solution configured with 1 g of tranexamic acid added to the physiological saline solution were injected into and around the incision before the closure of the wound in experimental group The same dose of saline were injected in the control group Hemoglobin,hematocrit,intraoperative blood loss,postoperative drainage,blood coagulation indexes such as D\|dimer and activated partial thromboplastin time before and after operation were compared between the two groups The number of blood transfusion,and observe the clinical symptoms of patients with lower extremity deep vein thrombosis ResultsThe postoperative hemoglobin,hematocrit,postoperative drainage and the number of blood transfusion in the experimental group were more significantly decreased than that in control group,the difference was statistically significant(P<005) No lower extremity deep vein thrombosis was found in both groups ConclusionTopical application of tranexamic acid can obviously reduce blood loss and blood transfusion after lumbar single segment fusion without increasing the risk of venous thrombosis of lower extremityKey Words:Tranexamic acid;Lumbar fusion;Bleeding;Thrombosis

 
基金项目:
作者简介:
参考文献:

 [1\]Park Y,Ha JW Comparison of one\|level posterior lumbar interbody fusion performed with a minimally invasive approach or a traditional open approach[J] Spine(Phila Pa 1976),2007,32:537\|543

[2]Smorgick Y,Baker KC,Bachison CC,et al Hidden blood loss during posterior spine fusion surgery[J] Spine J,2013,13:877\|881 
[3]Singh J,Ballal MS,Mitchell P,et al Effects of tranexamic acid on blood loss during total hip arthroplasty[J] J Orthop Surg(Hong Kong),2010,18:282\|286 
[4]Noordin S,Waters TS,Garbuz DS,et al Tranexamic acid reduces allogenic transfusion in revision hip arthroplasty[J] Clin Orthop Relat Res,2011,469:541\|546
 [5]Molloy DO,Archbold HA,Ogonda L,et al Comparison of topical fibrin spray and tranexamic acid on blood loss after total knee replacement:a prospective,randomized controlled trial[J] J Bone Joint Surg Br,2007,89:306\|309 
[6]胡云建,陶凤荣,王厚东,等D\|二聚体测定在肺栓塞诊断中的应用价值\[J\]中华检验医学杂志,2002,25(2):95\|97
[7]冯贵喜,刘军,张福江,等氨甲环酸局部应用对单侧全膝关节置换术后隐性失血量的影响\[J\]中华骨科杂志,2016,(3):151\|155
服务与反馈:
文章下载】【加入收藏
友情链接   中国知网-中国冶金工业医学杂志 搜狐邮箱 中国知网 中华预防医学会网站 国家新闻出版总署 博文采编官方网站 CNKI翻译助手 网易VIP163邮箱 网易126邮箱 网易163邮箱 雅虎邮箱 新浪邮箱 QQ邮箱 鞍钢总医院网站 丁香园 好医生 疾病查询

《中国冶金工业医学杂志》
编辑部地址:辽宁省鞍山市铁东区健身街3号(鞍钢总医院院内),邮编114002
电话:0412- 6327774 ,0412-6706630,传真:0412-6327774
网址:www.zgyjgyyxzz.com  邮箱:yjyx1984@vip.163.com
京ICP备10041176号