中国冶金工业医学杂志

念珠菌121株感染无菌体液的分布及耐药监测

作者：焦二莉

关键词：无菌体液念珠菌分布耐药监测

分类号：R 379.4

出版年,卷(期):页码：2018,35(5):506-509

摘要：

摘要：目的了解无菌体液中念珠菌属感染的临床分布特点，分析耐药情况，为临床合理应用抗真菌药提供依据。方法收集2012年1月～2017年8月临床无菌体液分离的念珠菌121株，对菌种进行鉴定和药敏实验，对数据进行分析。结果无菌体液中感染念珠菌主要有白色念珠菌、近平滑念珠菌、热带念珠菌、光滑念珠菌等。尿液及其他体液以感染白色念珠菌为主，血液以感染近平滑念珠菌为主；念珠菌属对唑类药物的敏感性最低，对非唑类药物尚可。结论无菌体液感染白色念珠菌和近平滑念珠菌居多，其他念珠菌有上升趋势；念珠菌属耐药株不断出现，5种抗真菌药物的敏感率不断变化。
关键词：无菌体液；念珠菌；分布；耐药监测

Abstract：Objective To understand the clinical distribution characteristics of candida infection in aseptic conditions, and to analyze the drug resistance and provide basis for the rational use of antifungal agents. Method A total of 121 strains of Candida isolated from clinical sterile body fluids were collected from January 2012 to August 2017. The French Merriot VITEK-2 Compact automatic microbiological identification system and the yeast antimicrobial test strip （ATB FUNGUL 3）, and the data were analyzed statistically. Results Sterile body infection of Candida was mainly Candida albicans, Candida parapsilosis, Candida tropicalis, Candida glabrata, etc. Among them, urine and other body fluids to infection Candida albicans mainly; while the blood to the infection Candida parapsilosis; Candida was the least sensitive to azole drugs, non-azole drugs can be okay. Conclusion Sterile body fluid infection Candida albicans and Candida albicans mostly, other Candida have an upward trend; Candida resistant strains are continuing go appear, five kinds of anti-fungal drug sensitivity rate is constantly changing.
Key Words：Sterile body fluids; Candida; Distributed; Drug resistance testing

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参考文献：

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