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电子期刊 >> 正文 |
| 血清内毒素及降钙素原对细菌感染性疾病的诊断价值 |
| 作者：王光瑛 王卫青 于武年 朱伟奇 冯翔 |
| 单位：内蒙古包钢医院重症医学科 内蒙古 包头 014010 |
| 关键词：内毒素 降钙素原 细菌感染性疾病 |
| 分类号：R 515 |
| 出版年,卷(期):页码：2019,36(1):5-6 |
| 摘要： |
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摘要：目的 探讨血清内毒素（ET）及降钙素原（PCT）对细菌感染性疾病的诊断价值。方法 将我院感染性疾病患者54例分为细菌感染组31例和非细菌感染组23例，分别采用动态浊度法及免疫荧光层析法测定血清ET和PCT水平。结果 细菌感染组ET、PCT水平显著高于非细菌感染组（t＝14.33、18.52，P＜0.01）。以ET≥0.1 EU/ml、PCT≥0.1 ng/ml为阳性标准，ET、PCT诊断细菌感染的灵敏度分别为90.3%、93.5%，特异度分别为91.3%、87.0%。结论 测定ET、PCT可明显区分细菌性和非细菌性感染，对于早期诊断细菌性感染具有临床价值。 |
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Abstract：Objective To investigate the value of plasma endotoxin（ET）and procalcitonin（PCT）levels in diagnosis of bacterial infectious diseases. Methods The levels of plasma ET and PCT were detected in the bacterial infection group（31 cases）and the non-bacterial infection group（23 cases）by kinetic turbidimetric assay and immunofluorescence chromatography respectively. Results The levels of ET and PCT in the bacterial infection group were significantly higher than those in the non-bacterial infection group（t＝14.33, 18.52, P＜0.01）. The sensitivity of applying ET and PCT for diagnosis of bacterial infection was 90.3% and 93.5%, and the specificity was 91.3% and 87.0% respectively（ET≥0.1 EU/ml, PCT≥0.1 ng/ml as positive standard）. Conclusion The plasma ET and PCT levels can distinguish bacterial and non-bacterial infections, which is of great significance for early diagnosis of bacterial infection. |
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［1］ Levy MM, Fink MP, Marshall JG, et al. 2001 SCCM/ESICM/ACCP/ATS/ |
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