Abstract:Objective To investigate the status of Helicobacter pylori(Hp)infection in population of health physical examination and its effect on
metabolism blood lipid and blood glucose. Methods The Hp infections in 1279 healthy subjects from January 2015 to December 2017 were detected
by 13C or 14C urea breath test(13C-UBT/14C -UBT)and the distribution characteristics of Hp infection were analyzed in terms of gender and age. The
body mass index(BMI), total cholesterol(TC), triglyceride(TG), high- density lipoprotein cholesterol(HDL- C), low- density lipoprotein cholesterol
(LDL-C), fasting blood glucose(FBG), Serum albumin(Alb), hemoglobin(Hb), and C reactive protein(CRP)were compared between Hp positive and
negative groups. Results The total infection rate of Hp in the physical examination population was 47.1%, including 49.3% for males and 44.4% for
females. There was no significant difference between males and females(P >0.05). The infection rates of Hp were different in all age groups, but no
significant differences(P >0.05 respectively). There were no significant differences between Hp positive and negative groups in BMI,TG , HDL-C, Hb,
and Alb(P >0.05 respectively). TC, LDL-C, FBG, and CRP in Hp-positive group were significantly higher than those in Hp-negative group(P <0.05
respectively). Conclusion There were some effects of Hp infection on blood lipids and blood glucose metabolism, but the further studies were still
needed.
Key Words:Helicobacter pylori; Breath test; Blood lipid; Blood glucose
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