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肥胖型多囊卵巢综合征患者早期先兆流产保胎结局临床研究
作者:王敬唯1 岳红萍2? 罗芳2 李寅2 端娅2 廉阳秧2 李霞2 
单位:1.大理大学临床医学院 云南 大理 671000 2.大理大学附属第二医院(云南省第三人民医院) 
关键词:关键词:多囊卵巢综合征 体重指数 先兆流产 
分类号:R 711.75
出版年,卷(期):页码:2020,37(6):625-626
摘要:

 摘要:目的 探讨肥胖型多囊卵巢综合征(PCOS)患者早期先兆流产保胎结局。方法 收集2016年1月至2019年6月PCOS孕早期先兆流产保胎病例,根据患者体重指数分组,BMI≥28 kg/m2为观察组,BMI<28 kg/m2为对照组。比较两组保胎成功率和妊娠期糖尿病(GDM)、妊娠期高血压的发生率。结果 对照组保胎成功率高于观察组,组间差异有统计学意义(P<0.05);观察组GDM和妊娠期高血压发生率均高于对照组,但组间差异均无统计学意义(均P>0.05)。结论 肥胖型PCOS患者早期先兆流产保胎成功率较非肥胖型患者低,妊娠结局相对较差,PCOS患者应积极调整生活方式、维持BMI在标准范围内,以降低流产率和减少妊娠合并症的发生。

 Abstract:Objective To investigate the outcomes of early threatened abortion in obese polycystic ovary syndrome(PCOS). Methods The cases who had threatened abortion in early pregnancy with PCOS from January 2016 to June 2019 were selected and divided according to BMI into the observation group with BMI≥28 kg/m2 and the control group with BMI<28 kg/m2. The pregnancy success rate, the incidence of GDM,the incidence of hypertension during pregnancy of two groups were compared. Results The pregnancy success rate of the control group was significantly higher than that of the observation group, the difference was statistically significant(P<0.05). Compared with the control group, the incidence of GDM and hypertension in the observation group were higher, but the difference was not statistically significant (all P>0.05). Conclusion The success rate of early threatened abortion in obese PCOS patients is lower than that in non-obese PCOS patients, and the pregnancy outcome is relatively poor. Therefore, PCOS patients should actively adjust their lifestyle and maintain their BMI within the standard range, to reduce the abortion rate and reduce the incidence of pregnancy complications.

基金项目:
作者简介:
参考文献:
参考文献
[1] 徐丛剑,华克勤.实用妇产科学[M]. 北京:人民卫生出版社,2018:506-517.
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[4] 丁文,郭艺红.调整生活方式对多囊卵巢综合征女性妊娠结局的影响[J]. 生殖医学杂志,2018,27(4):378-383.
[5] Matjila MJ,Hoffman A,van der Spuy ZM. Medical conditions associated with recurrent miscarriage:Is BMI the tip of the iceberg?[J]. European Journal of Obstetrics & Gynecology and Reproductive Biology,2017(214):91-96.
[6] Robker RL,Akison LK,Bennett BD,et al. Women exhibit differences in ovarian metabolites,hormones,and gene expression compared with moderate-weight women[J]. J Clin Endocrinol Metab,2009,94(5):1533-1540.
[7] Jacobsen BK,Knutsen SF,Oda K,et al. Obesity at age 20 and the risk of miscarriages,irregular periods and reported problems of becoming pregnant:the adventist health study-2[J]. Eur J Epidemiol,2012,27(12):923-931.
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