Abstract：Objective To  observe the clinical efficacy of self-made Jiangtang Qiangxin Recipe in the treatment of type 2 diabetes with heart failure. Methods A total of 60 patients with type 2 diabetes and heart failure diagnosed and treated in our hospital from January to September 2019 were divided into a control group and an observation group according to the random number tables,with 30 cases in each group. The patients in the control group were treated with conventional hypoglycemic combined with anti-heart failure treatment,and in the observation group were taking orally with self-made Jiangtang Qiangxin Recipeon the basis of the control group. Both groups were treated for 2 consecutive months. The levels of FPG, 2 hPG, HbA1c, LVEF, NT-ProBNP and adverse reactions before and after treatment were compared between the two groups. Results After treatment, FPG, 2 hPG, HbA1c and NT-ProBNP in the two groups were lower than before treatment and the reduction of FPG, 2 hPG and NT-ProBNP of the observation group were better than that of the control group. The differences between groups were statistically significant（both P＜0.05）, HbA1c were reduced but the difference between the two groups was not statistically significant（P＞0.05）; LVEF in the two groups was higher than before treatment, and the increase in the observation group was better than the control group, the difference between the two groups were statistically significant（P＜0.05）; the incidence of adverse reactions in the two groups were 36.67% and 16.67% respectively. Conclusion The self-made Jiangtang Qiangxin Recipe has significant clinical effect in the treatment of type 2 diabetes with heart failure, and is worthy of clinical research and promotion.