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电子期刊 >> 正文 |
摘要:
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白细胞介素(IL)是由免疫细胞或其他非免疫细胞产生的细胞因子,自1979年开始命名以来,随着分子生物学和细胞生物技术的迅速发展,先后发现了多种IL,目前已报导的有IL-1~IL-27.IL在调节免疫应答、抗肿瘤、造血、机体防御机制中起着重要的作用.
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参考文献:
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Castillo J.Moro MA.Blanco M The release of tumor necrosis factor-alpha is associated with ische mic tolerance in human stroke 2003(6) Kim HM.Shin HY.Jeong HJ Reduced IL-2 but elevated IL-4,IL-6,and IgE serum levels in patients with cerbral infarction during the acute stage 2000(3) Araujo DM.Lapchak PA.Collier B Localization of interleukin-2 immunoreactivity and interleukin-2 receptors in the rat brain:interaction with the cholinergic system 1999 Merrill JE IL-2 effects in the Central Neurous System 2000 Block F.Peters M.Nolden Kock M Expression of IL-6 in the ischemic penumbra 2000(5) Suzuki S.Tanaka K.Nogawa E Cerebral neurons.express interleukin-6 after transient forebrain ischemia in gerbils 1999(2) Gasche Y.Fujimura M.Morita-Fujimura Y Early appearance of activated matrix Metalloprteinese-9 after focal cerebral ische mia in mice.A possible role in blood-brain barrier dysfunction 1999 Vila N.Castillo J.Davalos A Proinflam matoty cytokins and early neurological worsening in ischemic stroke 2000(10) Juttler E.Tarabin V.Schwaninger M Interleukin-6(IL-6):a possible neuromodulator induced by neuronal activity 2002(3) Yu AC.Blau LT Expression ofinterleukin-1 alpha,tumornecrosis factor alpha and interleukin-6 genes in astrocytes under ischemic injury 2000(4-5) Herrmann O.Tarabin V.Suzuki S Regulation of body temperature and neuroprotection by endogenous interleukin-6 in cerebral ischemia 2003(4) Herrmann O.Tarabin V.Suzuki S Regulaion of body teperature and neuroprotection by endoge nous interleukin-6 in cerebral ischemia 2003(4) Dihne M.Block F Focal ischemia induces transient expression of IL-6 in the subsantia nigra pars reticulata 2001(1-2)
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