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电子期刊 >> 正文 |
| 妊娠高血压综合征患者血清瘦素水平的临床研究 |
| 作者：孙宛 尚涛 SUN Wan SHANG Tao |
| 单位：孙宛 SUN Wan(宁波新东方女子医院)尚涛 SHANG Tao(中国医科大学附属二院妇产科) |
| 关键词：妊娠 妊高征 瘦素 高血压 蛋白尿 |
| 分类号：R714.246 |
| 出版年,卷(期):页码：2006,23(5):0-0 |
| 摘要： |
| 目的:研究正常孕妇和PIH患者血清leptin水平与部分临床及生化指标的相关性.方法:采用放射免疫法测定血清leptin水平,应用SPSS软件进行统计学分析.结果:PIH患者血清leptin水平明显高于正常孕妇(P＜0.01),且中、重度PIH与轻度PIH血清leptin水平差异非常显著.孕妇血清leptin水平与BMI、MAP、收缩压、舒张压呈正相关(P＜0.01;P＜0.05).结论:PIH患者血压升高可能与leptin水平升高有关,血清leptin在预测PIH及其严重程度上具有一定的临床价值. |
| 基金项目： |
| 作者简介： |
| 参考文献： |
| 乐杰.谢辛.丰有吉 妇产科学 1997 Ahima RS.Saper CB.Flier JS Leptin regulatin of neuroendocrine Systems 2000(3) Anim-Nyame N.Sooranna SR.Steer PJ Longitudinal analysis of maternal plasma leptin concentrations during normal pregnancy and pre-eclampsia 2000(9) McCarthy JE.Misra DN.Roberts JM Maternal plasma leptin is increased in preeclampsia and positively correlates with fetal cord concentration 1999 Mise H.Sagawa N.Matsumoto T Augmevted placental production of leptin in preeclampsia:possible involvement of placental hypoxia 1998 Shek EW.Brands MW.Hall JE Chronic leptin infusion increases arterial pressure 1998 Suther PM.Locher R.Vetter W Is there a role for the obgene product leptin in essential hypertension? 1998(11) Laivuori H.Kaaja R.Koistinen H Leptin during and after preeclaimtic or normal pregnancy:its relation to serum insulin and insulin sensitivity 2000(2) |
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《中国冶金工业医学杂志》 |